Detox supplement for liver health

Support Liver (90 Caps)

$28.00

Optimize your liver’s ability to detoxify and purge toxins with a blend of powerful antioxidants, and amino acids that boost this critical organ’s health. †

  • NEW FORMULA RELEASED 4/2022
  • Enhance the liver’s natural ability to cleanse the blood and urine
  • Increase toxin removal and free-radical scavenging activity
  • Support the removal of harmful substances that may damage the liver

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Suggested Use

As a dietary supplement, take 3 capsules before breakfast or as recommended by your health care professional.

Ingredients

Three Capsules of Support Liver Contain:

L-Methionine – 300 mg
Artichoke Leaf Extract (5% Cyanrin) – 250 mg
L-Taurine – 250 mg
Milk Thistle Extract (80% Silymarin) – 250mg

Other Ingredients: Vegetable Capsule, Cellulose, Magnesium Stearate, Silicon Dioxide, Hypromellose

Allergen Information

Contains: Rice

Formulated to be free of: Egg, Dairy, Shellfish/Fish, Tree Nuts/Peanuts, Soy, Gluten, Bromelain, Corn, Artificial Colors, Artificial Flavors, Artificial Preservatives, Sodium, Sugar.

Liver Detox Support Supplement

The liver’s primary function involves promoting the removal of toxins and waste from the body. However, the liver also regulates the metabolism of things like bilirubin, hormones, drugs, and cholesterol. Additionally, the breakdown of proteins, carbohydrates, and fats occurs in the liver, along with enzyme activation. The production of important proteins and the storage of vitamins, minerals, and glycogen takes place in the liver as well. This vital organ supports optimal health and well-being when it is working properly. Respect it. And optimize your well-being.

Amino Acid/Botanical Liver Supplement

If the liver’s ability to carry out its critical processes becomes compromised, toxins, cholesterol, waste, and other harmful particles may quickly begin to accumulate in various parts of the body. Certain factors, such as an unhealthy diet, or consuming large amounts of alcohol regularly, can actually lead to an abundance of toxic particles the liver cannot process fast enough. Furthermore, processed foods, air and water pollution, alcohol, drugs, and many other substances like chemicals and heavy metals, bombard us with massive quantities of toxins on a routine basis.

Eating a nutritious, well-balanced diet is one of the best ways to ensure that the liver remains clean and fully functional. Taking a nutritional supplement with key micronutrients enhances this function by promoting whole body cleansing. Support Liver contains a combination of amino acids, enzymes, and antioxidants that help your liver to do its job against the odds of a toxic world. †

The Support Liver Advantage

Support Liver is formulated with compounds known to protect and restore the liver. We chose these four ingredients to form a cohesive, synergistic blend backed by decades of proven efficacy in supporting liver health and detoxification. †

  • Milk Thistle Extract (80% silymarin) – An antioxidant-rich herb that contains silymarin to assist your liver in toxin elimination and defense against harmful toxin by-products.
  • L-Methionine – An essential amino acid that plays an important role in the liver’s metabolism of nutrients. It also enhances the activity of antioxidants the body naturally produces such as glutathione.
  • L-Taurine – A sulfur-containing amino acid that is naturally found in high concentrations in the liver. It doubles as an antioxidant to help flush out liver toxins by regulating inflammatory signals that surround toxin-mediated liver damage.
  • Artichoke Leaf Extract (5% Cynarin) – Herb is rich in antioxidants like cynarin to fight liver damage by augmenting toxin clearance through bile and enhancing tissue regeneration for liver recovery. Well-studied to demonstrate abilities to protect and regenerate liver cells.

FAQ: Support Liver

Why did Support Liver’s formula change in 2022?

FDA changes put N-Acetyl-Cysteine at risk so we decided to not just replace that ingredient, but also update the formula based on feedback from clinicians.

I have impaired liver function. Can I take more than the suggested use amount?

The formula appears to be well-tolerated at higher than recommended dosages. We know of alcoholics in recovery, for example, who are taking as many as 9 capsules a day, to accelerate their liver repair. When in doubt, consult a qualified health professional with direct experience in detoxification.

The Formula: Science-Based Ingredients

Milk Thistle Extract – Herbalists and physicians alike used the milk thistle for hundreds of years to treat a wide range of liver pathology, including fatty liver disease, hepatitis, cirrhosis, and to protect the liver from environmental toxins. Today, millions of people consume milk thistle to support healthy liver function. Researchers have focused their efforts on studying silymarin, a mixture of flavonolignans extracted from milk thistle, and the most active ingredient of this extract, silybin. [1-4] Milk thistle exhibits its hepatoprotective properties by three major mechanisms: 1) serving as an antioxidant, 2) an anti-inflammatory, and 3) an antifibrotic substance. [2-4] The anti-inflammatory properties of milk thistle are attributable to its ability to regulate cytokines responsible for inducing inflammation. Milk thistle has been shown to down-regulate and inhibits the expression of COX-2, a key mediator of inflammatory pathways. [5]

L-Methionine – The body uses this essential amino acid to produce antioxidants including glutathione [6]. Healthy methionine levels also enhance liver metabolism of proteins and amino acids. This vital process involves breaking down these molecules to release key nutrients such as glucose (sugar) or healthy fats (lipids). Liver metabolism also promotes the removal of harmful substances (e.g., toxins, nitrogen) that may be attached to food molecules [7]. Accordingly, a methionine deficiency is linked to liver problems that can worsen complications for people suffering from poor liver function [8].

Taurine – In studies regarding poor liver health, taurine supplementation has been shown to raise liver taurine levels dramatically, which subsequently leads to better liver function [9]. Maintaining healthy levels of taurine also lowers the incidence of liver cell damage and reactive oxygen species (ROS) formation [9-10]. The buildup of ROS leads to oxidative stress that can damage cells, worsen fat accumulation, and cause various health problems. Taurine supplementation helps preserve liver function by targeting oxidative stress, supporting fat breakdown, heightening antioxidant enzyme activity, and boosting glutathione levels [9-10].

Artichoke Extract – Artichoke (Cynara scolymus) leaf extract (ALE) contains many phytonutrients that may have antioxidant and anti-inflammation activities against many diseases including liver damage. Artichoke has demonstrated antioxidant activity through decreased production of reactive oxygen species, decreased lipid peroxidation and increased activity of glutathione peroxidase. [11] Pooled analysis, of eight clinical trials, revealed that artichoke supplementation significantly reduced the concentration of aspartate aminotransferase (AST) and alanine transaminase (ALT), in comparison with placebo. [12] Subgroup analysis suggested that artichoke administration significantly reduces AST and ALT in patients with non-alcoholic fatty liver disease and ALT among overweight/obese subjects. [11-14]

References

  1. Loguercio C, Festi D. Silybin and the liver: from basic research to clinical practice. World J Gastroenterol. 2011 May 14;17(18):2288-301.
  2. Abenavoli L, Bellentani S. Milk thistle to treat non-alcoholic fatty liver disease: dream or reality? Expert Rev Gastroenterol Hepatol. 2013 Nov;7(8):677-9.
  3. Schümann J, Prockl J, Kiemer AK, Vollmar AM, Bang R, Tiegs G. Silibinin protects mice from T cell-dependent liver injury. J Hepatol. 2003 Sep;39(3):333-40.
  4. Wellington K, Jarvis B. Silymarin: a review of its clinical properties in the management of hepatic disorders. BioDrugs. 2001;15(7):465-89.
  5. Loguercio C, Nardi G, Argenzio F, et al. Effect of S-adenosyl-L-methionine administration on red blood cell cysteine and glutathione levels in alcoholic patients with and without liver disease. Alcohol 1994;29:597-604.
  6. Li Z, et al. Methionine metabolism in chronic liver diseases: an update on molecular mechanism and therapeutic implication. Signal Transduct Target Ther. 2020;5(1):280.
  7. Parcell S. Sulfur in human nutrition and applications in medicine. Altern Med Rev. 2002;7:22-44.
  8. Boucknooghe T, Remacle C, Reusens B. Is taurine a functional nutrient? Curr Opin Clin Nutr Metab Care. 2006;9:728-33.
  9. Xu YJ, et al. Review The potential health benefits of taurine in cardiovascular disease. Exp Clin Cardiol. 2008;13(2):57-65.
  10. Birdsall TC. Therapeutic applications of taurine. Altern Med Rev. 1998;3:128-36.
  11. Küskü-Kiraz Z., Mehmetçik G., Dogru-Abbasoglu S., Uysal M. Artichoke leaf extract reduces oxidative stress and lipoprotein dyshomeostasis in rats fed on high cholesterol diet. Phytotherapy Research. 2010;24(4):565–570. doi: 10.1002/ptr.2985.
  12. Zapolska-Downar D., Zapolski-Downar A., Naruszewicz M., Siennicka A., Krasnodbska B., Kolodziej B. Protective properties of artichoke (Cynara scolymus) against oxidative stress induced in cultured endothelial cells and monocytes. Life Sciences. 2002;71(24):2897–2908. doi: 10.1016/s0024-3205(02)02136-7.
  13. Vaya J., Aviram M. Nutritional antioxidants mechanisms of action, analyses of activities and medical applications. Current Medicinal Chemistry-Immunology, Endocrine & Metabolic Agents. 2001;1(1):99–117. doi: 10.2174/1568013013359168.
  14. Urquiaga I., Leighton F. Plant polyphenol antioxidants and oxidative stress. Biological Research. 2000;33(2):55–64

HIGH ABSORPTION

In order to deliver these nutrients to create benefits, there must be efficient absorption into the cells.

BIOAVAILABLE

Our formulas contain ingredients and co-factors which support the ability of nutrients to do work quickly.

PLANT-BASED

We use botanically sourced ingredients whenever possible, to provide your body with nature’s simplicity and efficacy.