Support blood sugar balance with botanicals

Support Glucose (60 Caps)


Balance blood sugar and boost metabolism with a formula packed with research-backed nutrients, including proprietary forms of cinnamon and chromium, as well as Gymnema and bitter melon. †

  • Promote healthy glucose levels, with compounds that support the regulation of glucose absorption and insulin release
  • Support a healthy diet with nutrients shown to alleviate volatile swings of blood glucose
  • Aids weight management with antioxidants and minerals that help to accelerate fat-burning metabolism
  • Not intended for diabetics unless under guidance of a physician

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Suggested Use

As a dietary supplement, take 1 capsule with food one to three times per day or as recommended by your health care professional.


One Capsule of Support Glucose Contain:

Chromium (as Cr Polynicotinate) – 200 mcg
Gymnema sylvestre Leaf Extract yielding 50 mg Gymnemic Acid – 200 mg
Cinnulin PF® (Cinnamon Extract) – 125 mg
Alpha-Lipoic Acid – 100 mg
Bitter Melon (Momordica charantia) Extract yielding 0.4 mg Charantin – 80 mg
Lagerstroemia Speciosa L. (Banaba) Leaf Extract yielding 0.5 mg Corosolic Acid – 50 mg
Vanadyl Sulfate – 5 mg

Other Ingredients: Microcrystalline Cellulose, Magnesium Stearate, Hypromellose

Allergen Information

Contains: No known allergens

Formulated to be free of: Egg, Dairy, Shellfish/Fish, Tree Nuts/Peanuts, Soy, Gluten, Bromelain, Corn, Artificial Colors, Artificial Flavors, Artificial Preservatives, Sodium, Sugar, Rice.

Supplement Support for Glycemic Control

Glucose is your body’s primary source of energy. It fuels reactions that optimize metabolism, exercise performance, immune system responses, CNS reactions and many other functions. Unstable glucose levels can lead to short-term symptoms such as dizziness, nausea, and weakness. Long-term symptoms include weight gain, loss of muscle tone, chronic fatigue, and even serious complications like heart and brain disease. Despite efforts to eat as healthy as possible, as we age our ability to maintain optimal glucose levels becomes harder. That’s where Support Glucose comes in.

Blood Sugar Support Supplementation

BioMatrix’ Support Glucose contains ingredients that have been extensively studied and are known to moderate the cellular activities of insulin and glucose. It is a potent product that aids glycemic control in individuals who have not been diagnosed with Type 1 or 2 diabetes. If you have diabetes or are concerned that you may be at risk of the disease, you should consult with a healthcare professional before taking this product. For those with blood glucose in healthy range, this may be just the formula you’ve been seeking to sharpen your metabolic edge. †

The Support Glucose Advantage

Support Glucose supports glucose balance by optimizing glucose absorption and uptake by cells, insulin release, and nutrient-converting metabolic reactions. Additionally, the ingredients serve to curb inflammation while also protecting your heart and brain cells from oxidative stress, thanks to strong antioxidant properties. †

The Ingredients: Purpose

  • ChromeMate® Chromium Polynicotinate – A trace mineral bound to niacin to promote glucose utilization, defend against insulin resistance and fat metabolism. Individuals with insufficient levels of biologically active chromium are likely to have excess insulin sensitivity.
  • Gymnema Sylvestre Leaf – Supports weight management by defending against cravings for sweets, stimulating pancreatic insulin release, and balancing post-meal sugar absorption, cholesterol levels, and inflammation.
  • Cinnulin PF® Cinnamon – A potent cinnamon bark extract rich in Type A polymers that target insulin signaling pathways to support healthy blood sugar levels and fat usage.
  • Alpha-Lipoic Acid – An antioxidant-rich omega-3 fatty acid that supports cardiovascular and nerve health by scavenging harmful free radicals, enhancing insulin sensitivity, and serving as a cofactor for metabolic reactions.
  • Bitter Melon – Native to India, this extract is enriched with charantin, which supports glycemic control, glucose storage, and weight management.
  • Banaba Leaf Extract – This extract is rich in corosolic acid, an antioxidant that supports insulin sensitivity, glucose utilization, weight management, and inflammatory molecule balance.
  • Vanadyl Sulfate – A trace mineral that regulates glucose entry into cells and acts as a cofactor for essential glucose-regulating metabolic reactions

FAQ: Support Glucose

Is this only helpful for those with elevated glucose levels or is it also helpful for those with low glucose/hypoglycemia?

It is intended to help with glucose metabolism, in general. Under FDA regulations we cannot say if a dietary supplement can or cannot influence levels of glucose.

Is there a recommendation for those with diabetes or other glucose issues?

A disclaimer often used for products like this: This product should only be used with careful monitoring of blood sugar levels and in consultation with your healthcare practitioner. If pregnant or nursing consult your healthcare practitioner before taking this product.

Science-Based Ingredients

  • ChromeMate® Niacin bound Chromium (as Cr Polynicotinate) – Chromium is a trace mineral heavily involved in glucose metabolism. Research suggests that supplementing with chromium picolinate may help support insulin sensitivity by targeting a critical inflammatory molecule called tumor necrosis factor-α [1]. Research also shows that chromium supplementation may significantly increase levels of “good cholesterol” known as HDL while decreasing levels of” bad cholesterol” known as LDL [2]. Studies indicate that chromium supplementation may significantly improve carbohydrate craving, indicating a potential role in weight management [3]. Clinical research suggests that when chromium and niacin form a complex, chromium can more powerfully exert each of these effects [4].
  • Gymnema Sylvestre Leaf Extract – Native to India, Africa, and Australia, this extract has been used in Ayurvedic medicine for centuries and is enriched with gymnemic acid. In a study that examined supplementation with this potent extract, patients experienced significantly reduced HbA1c and glucose levels, indicating a potential increase in insulin sensitivity [5]. In another study, patients who were supplemented with gymnema sylvestre extract for eight weeks experienced a significant reduction in body weight, cholesterol levels, and LDL levels [6]. Studies also indicate that supplementing with this extract may help dampen a patient’s cravings for sweets [7].
  • Cinnulin PF® Cinnamon Extract – This proprietary water extract is derived from Cinnamomum burmannii through an enhanced process that filters out toxins that are found within whole cinnamon. This form of cinnamon is particularly beneficial since it is rich in Type A polymers, which help to promote cardiovascular health. One study found that patients who supplemented with Cinnulin PF® for 12 weeks experienced significantly improved fasting blood glucose levels [8].
  • Alpha-Lipoic Acid – This fatty acid plays a crucial and multifaceted role in glucose metabolism. It bridges two critical reactions that convert glucose into energy while also scavenging and neutralizing harmful oxygen radicals. One study showed that supplementing with alpha-lipoic acid for eight weeks significantly reduced fasting blood glucose, post-meal blood glucose, and indicators of insulin resistance [9].
  • Bitter Melon (Momordica charantia) Extract – Bitter melon has been used for centuries in traditional Chinese and Ayurvedic medicine for various ailments. In one study where participants were supplemented with bitter melon extract for three months, participants experienced significantly increased insulin secretion with simultaneous significant reductions in weight, waist circumference, blood glucose levels, and HbA1c [10].
  • Lagerstroemia speciosa L. (Banaba) Leaf Extract – Native to Southeast Asia, this extract contains an antioxidant called corosolic acid, which promotes cardiovascular health by targeting inflammation-causing free radicals, enhancing glucose transport, and balancing cholesterol levels. Studies have shown significant reductions in blood glucose when participants underwent oral glucose tolerance tests after supplementing with corosolic acid [11]. Additionally, patients who were supplemented with regimens including Banaba leaf extract were found to exhibit significant improvements in triglyceride and HDL levels [12].
  • Vanadyl Sulfate – This trace mineral has been found to exhibit profound effects on glucose control. In one study, participants who were supplemented with vanadyl sulfate for three weeks experienced significantly reduced blood glucose levels and enhanced peripheral insulin sensitivity [13].


  1. Imanparast F, Javaheri J, Kamankesh F, et al. The effects of chromium and vitamin D3 co-supplementation on insulin resistance and tumor necrosis factor-alpha in type 2 diabetes: a randomized placebo-controlled trial. Appl Physiol Nutr Metab. 2020;45(5):471-477. doi:10.1139/apnm-2019-0113
  2. Press RI, Geller J, Evans GW. The effect of chromium picolinate on serum cholesterol and apolipoprotein fractions in human subjects. West J Med. 1990;152(1):41-45.
  3. Docherty JP, Sack DA, Roffman M, Finch M, Komorowski JR. A double-blind, placebo-controlled, exploratory trial of chromium picolinate in atypical depression: effect on carbohydrate craving. J Psychiatr Pract. 2005;11(5):302-314. doi:10.1097/00131746-200509000-00004
  4. Urberg M, Zemel MB. Evidence for synergism between chromium and nicotinic acid in the control of glucose tolerance in elderly humans. Metabolism. 1987;36(9):896-899. doi:10.1016/0026-0495(87)90100-4
  5. Gaytán Martínez LA, Sánchez-Ruiz LA, Zuñiga LY, González-Ortiz M, Martínez-Abundis E. Effect of Gymnema sylvestre Administration on Glycemic Control, Insulin Secretion, and Insulin Sensitivity in Patients with Impaired Glucose Tolerance. J Med Food. 2021;24(1):28-32. doi:10.1089/jmf.2020.0024
  6. Preuss HG, Bagchi D, Bagchi M, Rao CV, Dey DK, Satyanarayana S. Effects of a natural extract of (-)-hydroxycitric acid (HCA-SX) and a combination of HCA-SX plus niacin-bound chromium and Gymnema sylvestre extract on weight loss. Diabetes Obes Metab. 2004;6(3):171-180. doi:10.1111/j.1462-8902.2004.00328.x
  7. Brala PM, Hagen RL. Effects of sweetness perception and caloric value of a preload on short term intake. Physiol Behav. 1983;30(1):1-9. doi:10.1016/0031-9384(83)90030-6
  8. Ziegenfuss TN, Hofheins JE, Mendel RW, Landis J, Anderson RA. Effects of a water-soluble cinnamon extract on body composition and features of the metabolic syndrome in pre-diabetic men and women. J Int Soc Sports Nutr. 2006;3(2):45-53. Published 2006 Dec 28. doi:10.1186/1550-2783-3-2-45
  9. Ansar H, Mazloom Z, Kazemi F, Hejazi N. Effect of alpha-lipoic acid on blood glucose, insulin resistance and glutathione peroxidase of type 2 diabetic patients. Saudi Med J. 2011;32(6):584-588.
  10. Cortez-Navarrete M, Martínez-Abundis E, Pérez-Rubio KG, González-Ortiz M, Méndez-Del Villar M. Momordica charantia Administration Improves Insulin Secretion in Type 2 Diabetes Mellitus. J Med Food. 2018;21(7):672-677. doi:10.1089/jmf.2017.0114
  11. Fukushima M, Matsuyama F, Ueda N, et al. Effect of corosolic acid on postchallenge plasma glucose levels. Diabetes Res Clin Pract. 2006;73(2):174-177. doi:10.1016/j.diabres.2006.01.010
  12. Cicero AFG, Fogacci F, Morbini M, et al. Nutraceutical Effects on Glucose and Lipid Metabolism in Patients with Impaired Fasting Glucose: A Pilot, Double-Blind, Placebo-Controlled, Randomized Clinical Trial on a Combined Product. High Blood Press Cardiovasc Prev. 2017;24(3):283-288. doi:10.1007/s40292-017-0206-3
  13. Halberstam M, Cohen N, Shlimovich P, Rossetti L, Shamoon H. Oral vanadyl sulfate improves insulin sensitivity in NIDDM but not in obese nondiabetic subjects [published correction appears in Diabetes 1996 Sep;45(9):1285]. Diabetes. 1996;45(5):659-666. doi:10.2337/diab.45.5.659


In order to deliver these nutrients to create benefits, there must be efficient absorption into the cells.


Our formulas contain ingredients and co-factors which support the ability of nutrients to do work quickly.


We use botanically sourced ingredients whenever possible, to provide your body with nature’s simplicity and efficacy.